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Toxic Potency Measurement for Fire Hazard Analysis.

pdf icon Toxic Potency Measurement for Fire Hazard Analysis. (7782 K)
Babrauskas, V.; Levin, B. C.; Gann, R. G.; Paabo, M.; Harris, R. H., Jr.; Peacock, R. D.; Yusa, S.

NIST SP 827; 119 p. December 1991.

Fire Retardant Chemicals Association. Technical and Marketing Issues Impacting the Fire Safety of Electrical, Electronic and Composite Applications. October 20-23, 1991, Coronado, CA, Fire Retardant Chemicals Assoc., Lancaster, PA, 151-155 pp, 1991.

Available from:

National Technical Information Service (NTIS), Technology Administration, U.S. Department of Commerce, Springfield, VA 22161.
Telephone: 1-800-553-6847 or 703-605-6000;
Fax: 703-605-6900.
Order number: PB92-137546


fire hazard analysis; toxicity test methods; building fires; computer models; fire models; death; N-gas model; radiant heating; smoke toxicity; radiant panel test method


A comprehensive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. This description of the methodology comprises: determination that the post-flashover fire is the proper focus of smoke inhalation deaths; criteria for a useful bench-scale toxic potency (LC50) measurement method; a method which meets these criteria, especially validation against real-scale fires; a computational procedure for correcting the results for the CO levels observed in real-scale post-flashover fires; procedures for reducing the usage of animals and broadening the applicability of data by interpreting gas measurement data using the N-Gas Model; and a procedure for identifying whether a product produces smoke within the ordinary range of toxic potency for post-flashover fires.